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Articles (62)
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The Fallback Procedure for Evaluating a Single Family of Hypotheses

Wiens, Brian L., Dmitrienko, Alexei

Journal:

Journal of Biopharmaceutical Statistics

Année:

2005

Langue:

english

Fichier:

PDF, 241 KB

english, 2005

General Multistage Gatekeeping Procedures

Alex Dmitrienko, Ajit C. Tamhane, Brian L. Wiens

Journal:

Biometrical Journal

Année:

2008

Langue:

english

Fichier:

PDF, 116 KB

english, 2008

Duration of protection from clinical hepatitis A disease after vaccination with VAQTA®

Wiens, Brian L., Bohidar, Norman R., Pigeon, Joseph G., Egan, James, Hurni, William, Brown, Leora, Kuter, Barbara J., Nalin, David R.

Journal:

Journal of Medical Virology

Année:

1996

Langue:

english

Fichier:

PDF, 755 KB

english, 1996

Tree-structured gatekeeping tests in clinical trials with hierarchically ordered multiple objectives

Alex Dmitrienko, Brian L. Wiens, Ajit C. Tamhane, Xin Wang

Journal:

Statistics in Medicine

Année:

2007

Langue:

english

Fichier:

PDF, 181 KB

english, 2007

Niche conservatism as an emerging principle in ecology and conservation biology

John J. Wiens, David D. Ackerly, Andrew P. Allen, Brian L. Anacker, Lauren B. Buckley, Howard V. Cornell, Ellen I. Damschen, T. Jonathan Davies, John-Arvid Grytnes, Susan P. Harrison, Bradford A. Hawk

Journal:

Ecology Letters

Année:

2010

Langue:

english

Fichier:

PDF, 298 KB

english, 2010

On Selecting a Multiple Comparison Procedure for Analysis of a Clinical Trial: Fallback, Fixed Sequence, and Related Procedures

Wiens, Brian L., Dmitrienko, Alexei

Journal:

Statistics in Biopharmaceutical Research

Année:

2010

Langue:

english

Fichier:

PDF, 381 KB

english, 2010

Prevalence of Ethanol Use Among Pregnant Women in Southwestern Uganda

English, Lacey, Mugyenyi, Godfrey R., Ngonzi, Joseph, Kiwanuka, Gertrude, Nightingale, Ira, Koren, Gideon, MacLeod, Stuart, Grunau, Brian E., Wiens, Matthew O.

Journal:

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC

Année:

2015

Langue:

english

Fichier:

PDF, 674 KB

english, 2015

Active management of atrial fibrillation or flutter in emergency department patients with renal impairment is associated with a higher risk of adverse events and treatment failure

Scheuermeyer, Frank X., Wong, Hubert, Barrett, Tyler W., Christenson, Jim, Grafstein, Eric, Grunau, Brian, Wiens, Matt, Innes, Grant

Journal:

CJEM

Année:

2019

Fichier:

PDF, 321 KB

2019

The Impact of Major Events on Ongoing Non-inferiority Trials, With Application to COVID-19

Wiens, Brian L., Lipkovich, Ilya

Journal:

Statistics in Biopharmaceutical Research

Année:

2020

Fichier:

PDF, 737 KB

2020

Response of canola, wheat, and pea to foliar phosphorus fertilization at a phosphorus-deficient site in eastern Saskatchewan

Froese, S., Wiens, J.T., Warkentin, T., Schoenau, J.J., Beres, Brian

Journal:

Canadian Journal of Plant Science

Année:

2020

Fichier:

PDF, 340 KB

2020

Randomization as a basis for inference in noninferiority trials

Brian L. Wiens

Journal:

Pharmaceutical Statistics

Année:

2006

Langue:

english

Fichier:

PDF, 147 KB

english, 2006

A fixed sequence Bonferroni procedure for testing multiple endpoints

Brian L. Wiens

Journal:

Pharmaceutical Statistics

Année:

2003

Langue:

english

Fichier:

PDF, 124 KB

english, 2003

A note on tree gatekeeping procedures in clinical trials

Alex Dmitrienko, Ajit C. Tamhane, Lingyun Liu, Brian L. Wiens

Journal:

Statistics in Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 74 KB

english, 2008

Randomized Controlled Trial of Intravenous Dexamethasone to Prevent Relapse in Acute Migraine Headache

Brian H. Rowe, Ian Colman, Marcia L. Edmonds, Sandra Blitz, Alan Walker, Sheldon Wiens

Journal:

Headache: The Journal of Head and Face Pain

Année:

2008

Langue:

english

Fichier:

PDF, 162 KB

english, 2008

Colonoscopic screening

Brian M. Stephenson, Paul J. Finan, D. Timothy Bishop, William J. Orrom, Ernest Wiens

Journal:

Diseases of the Colon & Rectum

Année:

1990

Langue:

english

Fichier:

PDF, 178 KB

english, 1990

Atmospheric transport of lindane (γ-hexachlorocyclohexane) from the Canadian prairies—a possible source for the Canadian Great Lakes, Arctic and Rocky mountains

Don T. Waite, Fraser G. Hunter (Retired), Brian J. Wiens

Journal:

Atmospheric Environment

Année:

2005

Langue:

english

Fichier:

PDF, 292 KB

english, 2005

Ambient air total gaseous mercury concentrations in the vicinity of coal-fired power plants in Alberta, Canada

Maxwell Mazur, Rachel Mintz, Monique Lapalme, Brian Wiens

Journal:

Science of The Total Environment

Année:

2009

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2009

Gentropy: evolving 2D textures

Andrea L. Wiens, Brian J. Ross

Journal:

Computers & Graphics

Année:

2002

Langue:

english

Fichier:

PDF, 502 KB

english, 2002

Choosing an equivalence limit for noninferiority or equivalence studies

Brian L. Wiens

Journal:

Controlled Clinical Trials

Année:

2002

Langue:

english

Fichier:

PDF, 80 KB

english, 2002

Design and Analysis of Three Treatment Equivalence Trials

Brian L. Wiens, Boris Iglewicz

Journal:

Controlled Clinical Trials

Année:

2000

Langue:

english

Fichier:

PDF, 151 KB

english, 2000

Precardiac mesoderm differentiation in vitro: Actin-isotype synthetic transitions, myofibrillogenesis, initiation of heartbeat, and the possible involvement of collagen

Darrell Wiens, Mark Sullins, Brian S. Spooner

Journal:

Differentiation

Année:

1984

Langue:

english

Fichier:

PDF, 4.60 MB

english, 1984

Precardiac mesoderm differentiation in vitro: Actin-isotype synthetic transitions, myofibrillogenesis, initiation of heartbeat, and the possible involvement of collagen

Darrell Wiens, Mark Sullins, Brian S. Spooner

Journal:

Differentiation

Année:

1985

Fichier:

PDF, 30 KB

1985

Efficacy and Safety of Darusentan in Patients With Resistant Hypertension: Results From a Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Study

Henry R. Black, George L. Bakris, Michael A. Weber, Robert Weiss, Mahfouz El Shahawy, Richard Marple, Georges Tannoury, Stuart Linas, Brian L. Wiens, Jennifer V. Linseman, Robert Roden, Michael J. Ger

Journal:

Journal of Clinical Hypertension

Année:

2007

Langue:

english

Fichier:

PDF, 246 KB

english, 2007

Application of computerized exercise ECG digitization: Interpretation in large clinical trials

Dennis G. Caralis, Leslee Shaw, Brian Bilgere, Liwa Younis, Karen Stocke, Robert D. Wiens, Bernard R. Chaitman

Journal:

Journal of Electrocardiology

Année:

1992

Langue:

english

Fichier:

PDF, 1.69 MB

english, 1992

Antibody responses of healthy infants to a recombinant hepatitis B vaccine administered at two, four, and twelve or fifteen months of age

Harry L. Keyserling, David J. West, Teresa M. Hesley, Caminade Bosley, Brian L. Wiens, Gary B. Calandra

Journal:

The Journal of Pediatrics

Année:

1994

Langue:

english

Fichier:

PDF, 251 KB

english, 1994

A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial

Michael A Weber, Henry Black, George Bakris, Henry Krum, Stuart Linas, Robert Weiss, Jennifer V Linseman, Brian L Wiens, Marshelle S Warren, Lars H Lindholm

Journal:

The Lancet

Année:

2009

Langue:

english

Fichier:

PDF, 216 KB

english, 2009

Worldwide experience with the CR326F-derived inactivated hepatitis A virus vaccine in pediatric and adult populations: an overview

David R. Nalin, Barbara J. Kuter, Leora Brown, Carol Patterson, Gary B. Calandra, Alan Werzberger, Daniel Shouval, Edward Ellerbeck, Stanley L. Block, Robert Bishop, Brian Wiens, Skai W. Schwartz, Joh

Journal:

Journal of Hepatology

Année:

1993

Langue:

english

Fichier:

PDF, 370 KB

english, 1993

Anatomy of a trial: a historical view of the Monroe inactivated hepatitis A protective efficacy trial

Alan Werzberger, Barbara Kuter, Daniel Shouval, Barbara Mensch, Leora Brown, Brian Wiens, John Lewis, William Miller, Robert Sitrin, Philip Provost, David Nalin

Journal:

Journal of Hepatology

Année:

1993

Langue:

english

Fichier:

PDF, 619 KB

english, 1993

Application of computerized exercise electrocardiogram digitizationinterpretation in large clinical trials

Mary Haueisen, Leslee Shaw, Brian Bilgere, Liwa Younis, Karen Stocke, Robert D. Wiens, Dennis Caralis, Bernard R. Chaitman

Journal:

Journal of the American College of Cardiology

Année:

1990

Langue:

english

Fichier:

PDF, 254 KB

english, 1990

A Controlled Trial of a Formalin-Inactivated Hepatitis A Vaccine in Healthy Children

Werzberger, Alan, Mensch, Barbara, Kuter, Barbara, Brown, Leora, Lewis, John, Sitrin, Robert, Miller, William, Shouval, Daniel, Wiens, Brian, Calandra, Gary, Ryan, John, Provost, Philip, Nalin, David

Journal:

Boston Medical and Surgical Journal

Année:

1992

Langue:

english

Fichier:

PDF, 902 KB

english, 1992

Incidence of Clinically Important Biphasic Reactions in Emergency Department Patients With Allergic Reactions or Anaphylaxis

Grunau, Brian E., Li, Jennifer, Yi, Tae Won, Stenstrom, Robert, Grafstein, Eric, Wiens, Matthew O., Schellenberg, R. Robert, Scheuermeyer, Frank Xavier

Journal:

Annals of Emergency Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2014

Effect of tin on sintering of iron powder compacts

Grunau, Brian E., Li, Jennifer, Yi, Tae Won, Stenstrom, Robert, Grafstein, Eric, Wiens, Matthew O., Schellenberg, R. Robert, Scheuermeyer, Frank Xavier

Journal:

Metal Powder Report

Année:

1990

Langue:

english

Fichier:

PDF, 103 KB

english, 1990

QUALITY CONTROL OF ONCOLOGY CLINICAL TRIALS

Meyerson, Laura J., Wiens, Brian L., LaVange, Lisa M., Koutsoukos, Antonis D.

Journal:

Hematology/Oncology Clinics of North America

Année:

2000

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2000

Missing Data in Noninferiority Trials

Wiens, Brian L., Rosenkranz, Gerd K.

Journal:

Statistics in Biopharmaceutical Research

Année:

2013

Langue:

english

Fichier:

PDF, 310 KB

english, 2013

Nuclear magnetic resonance study of lysozyme inhibition. Effects of dimerization and pH on saccharide binding

Sykes, Brian D., Studebaker, Joel F., Wien, Richard

Journal:

Journal of the American Chemical Society

Année:

1971

Langue:

english

Fichier:

PDF, 727 KB

english, 1971

Selection of Hypothesis Weights and Ordering When Testing Multiple Hypotheses in Clinical Trials

Wiens, Brian L., Dmitrienko, Alex, Marchenko, Olga

Journal:

Journal of Biopharmaceutical Statistics

Année:

2013

Langue:

english

Fichier:

PDF, 341 KB

english, 2013

ON TESTING EQUIVALENCE OF THREE POPULATIONS

Wiens, Brian L., Iglewicz, Boris

Journal:

Journal of Biopharmaceutical Statistics

Année:

1999

Langue:

english

Fichier:

PDF, 209 KB

english, 1999

Testing for Interaction in Studies of Noninferiority

Wiens, Brian L., Heyse, Joseph F.

Journal:

Journal of Biopharmaceutical Statistics

Année:

2003

Langue:

english

Fichier:

PDF, 221 KB

english, 2003

When Log-Normal and Gamma Models Give Different Results: A Case Study

Wiens, Brian L.

Journal:

The American Statistician

Année:

1999

Langue:

english

Fichier:

PDF, 555 KB

english, 1999

Assessing the Impact of Endpoint Shopping on Power in Confirmatory Clinical Trials

Wiens, Brian L.

Journal:

Journal of Biopharmaceutical Statistics

Année:

2003

Langue:

english

Fichier:

PDF, 163 KB

english, 2003

When Log-Normal and Gamma Models Give Different Results: A Case Study

Brian L. Wiens

Journal:

The American Statistician

Année:

1999

Langue:

english

Fichier:

PDF, 724 KB

english, 1999

Characteristics and Thirty-day Outcomes of Emergency Department Patients With Elevated Creatine Kinase

Grunau, Brian E., Pourvali, Reza, Wiens, Matthew O., Levin, Adeera, Li, Jennifer, Grafstein, Eric, Joo, Dan, Scheuermeyer, Frank Xavier, O'Neil, Brian J.

Journal:

Academic Emergency Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 285 KB

english, 2014

A Review of: “ Testing Statistical Hypotheses of Equivalence and Noninferiority , Second Edition, by S. Wellek”

Wiens, Brian

Journal:

Journal of Biopharmaceutical Statistics

Année:

2011

Langue:

english

Fichier:

PDF, 77 KB

english, 2011

Handbook of Statistical Distributions with Applicationsby K. Krishnamoorthy

Review by: Brian Wiens

Journal:

The American Statistician

Année:

2007

Langue:

english

Fichier:

PDF, 340 KB

english, 2007

Emergency Department Corticosteroid Use for Allergy or Anaphylaxis Is Not Associated With Decreased Relapses

Grunau, Brian E., Wiens, Matthew O., Rowe, Brian H., McKay, Rachel, Li, Jennifer, Yi, Tae Won, Stenstrom, Robert, Schellenberg, R. Robert, Grafstein, Eric, Scheuermeyer, Frank X.

Journal:

Annals of Emergency Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 905 KB

english, 2015

Multiple Testing Procedures in Two Pivotal Clinical Trials for Approval of a New Pharmaceutical Product

Wiens, Brian L.

Journal:

Journal of Biopharmaceutical Statistics

Année:

2011

Langue:

english

Fichier:

PDF, 194 KB

english, 2011

Simulated Microgravity and Hypergravity Attenuate Heart Tissue Development in Explant Culture

Lwigale, Peter Y., Thurmond, Joel E., Norton, William N., Spooner, Brian S., Wiens, Darrell J.

Journal:

Cells Tissues Organs

Année:

2000

Langue:

english

Fichier:

PDF, 717 KB

english, 2000

Fallback Tests in Dose-Response Clinical Trials

Dmitrienko, Alex, Wiens, Brian, Westfall, Peter

Journal:

Journal of Biopharmaceutical Statistics

Année:

2006

Langue:

english

Fichier:

PDF, 708 KB

english, 2006

Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity

Siegal, Deborah M., Curnutte, John T., Connolly, Stuart J., Lu, Genmin, Conley, Pamela B., Wiens, Brian L., Mathur, Vandana S., Castillo, Janice, Bronson, Michele D., Leeds, Janet M., Mar, Florie A.,

Journal:

New England Journal of Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 470 KB

english, 2015

Safety, tolerability and immunogenicity of a formalin-inactivated hepatitis A vaccine (VAQTA$) in rurual Kentucky children

BLOCK, STAN L., HEDRICK, JAMES A., TYLER, RONALD D., SMITH, R. ALAN, CALANDRA, GARY, PATTERSON, CAROLYN, LEWIS, JOHN, SITRIN, ROBERT, MILLER, WILLIAM, SCHWARTZ, SKAI, WIENS, BRIAN, NALIN, DAVID

Journal:

Pediatric Infectious Disease Journal

Année:

1993

Fichier:

PDF, 518 KB

1993